DOUBLE BLIND STUDY WITH ANTIDEPRESSIVE, SHORT PSYCHOTHERAPY AND PLACEBO IN PATIENTS WITH MILD TO MODERATE DEPRESSION

Jaime López Rodríguez*, Marco Antonio López Butrón**, Blanca Estela Vargas Terrez*, Valerio Villamil Salcedo*

Depression is one of the most common mental disorders in the world, and its prevalence is 8-12%. In Mexico it has been calculated that 8.3% of the population has suffered from this disorder at least once in their life. Regardless of country or culture, depression is two to three times more common in women than in men, and is suffered more by people who are single, separated, or divorced, or who live in rural areas. Although it can occur at any age, in 50% of the subjects the disorder begins between the ages of 20 and 50. The etiology of depression is multifactorial because biological, genetic, and psychosocial factors intervene that, to a greater or lesser degree, trigger the disease or exacerbate its symptoms.

From the psychoanalytic point of view, Freud postulated that the anger of depressed patients was directed towards their own interior by an identification with the lost object, since it was the only way that the “self” had to renounce the object. In this sense, new psychological theories of depression emerged and, therefore, a new approach to its treatment